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It’s Dr. Mario for an intense new challenge! Mario throws multi-colored vitamin capsules into a bottle that contains an ugly variety of nasty viruses. You can move, shift or spin capsules as they fall. Arrange them to align with other capsules on top of the virus. If you can get four or more of the same color in a row, POOF! They disappear! Destroy all of the viruses in the bottle and you progress to the next round where things get even more difficult!

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Frigid winter winds swept over an already chilled Gotham City. Random street crimes were running at an all-time high, despite the holidays. Down below, in the city’s frozen sewers, Oswald Cobblepot, known as The Penguin, planned more mayhem and schemed the take over of the fightened metropolis. His loyal army of missle-packing Penguin Commandos and the bizarre Red Triangle Circus Gang are energized by the evil genius of the web-footed orphan. A desperate call to Batman goes up. Partner with Batman to salvage Gotham City from The Penguin’s cold-hearted plot. Guide him in swift, life-like moves from …

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Following the annihilation of the Mad Gear Gang, a new criminal element named the Skull Cross Gang emerges as the new dominant street gang in Metro City. When Guy returns to Metro City from his martial art training to become reacquainted with his friend Mike Haggar, the Mayor of Metro City, the two are suddenly informed that the Skull Cross Gang has started a riot in the downtown area of the city. Joined by Lucia, a detective in the Metro City Police’s Special Crimes Unit, and Dean, a street fighter whose family was murdered by the Skull Cross Gang, Guy and Haggar must once again save Metro City from its newest menace.

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The MAD GEAR gang is back. They have kidnapped Guy’s fiancee (Guy was one of the main characters in the original game), her father and Guy’s martial arts master Genryusai. The younger sister of Guy’s fiancee, Maki, teams up with Mike Haggar and Carlos Miyamoto to take out the MAD GEAR gang once and for all. The game is set in various stages around the world.